Recruitment plans fail when they rely on optimism. Here is how to build plans that are grounded in data and ethics.
Recruitment is the most common reason clinical trials fall behind schedule. The good news is that most shortfalls can be anticipated with honest planning.
Start with real numbers
Use site patient databases and screening logs from similar studies, not estimates. Apply each major eligibility criterion to see how the pool narrows.
Use multiple channels
Combine investigator databases, physician referrals, patient support groups and ethics-approved awareness materials.
Make participation easier
Flexible visit scheduling, travel support and clear communication in local languages improve both enrollment and retention.
Track and adapt weekly
Monitor screening and screen-failure reasons every week and adjust the plan early, before small gaps become large delays.